This peptides are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases.ï¾ Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.
