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Purified anti-human CD62E;Isotype:Mouse IgG2a, κ;Reactivity:Human;Clone#:HCD62E;Application:FC   

详细描述

Antibodies Single
Sony
HCD62E
Flow Cytometry
Mouse IgG2a, κ
Human
Purified anti-human CD62E
Description CD62E (also known as E-selectin, ELAM-1, and LECAM-1) is a 115 kD type I membrane protein and a member of the selectin family. CD62E is highly expressed on activated endothelial cells (IL-2, TNF-α, other cytokines can increase expression) and can also be expressed on endothelial cells in the skin, bone marrow and placenta. CD62E is involved in tethering and leucocyte rolling on activated endothelium at inflammatory sites and may also play a role in tumor metastasis and angiogenesis. CD62E binds to both Siayl Lewis X (CD15s) and PSGL-1 (CD162). The HCD62E antibody has been shown to recognize human CD62E and to be useful for flow cytometry.
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Recommended Usage Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 microg per 10 cells in 100 microL volume or 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
References

1. Kaplan RC, et al. 2011. J. Infect Dis. 10:76. PubMed
2. Lutz CT, et al. 2011. J. Immunol. 186:4590. PubMed
3. Leeansyah E, et al. 2013. Blood. 121:1124. PubMed
4. Simmons R, et al. 2013. J Virol. 87:3087. PubMed
5. Kurktschiev PD, et al. 2014. J Exp Med. 211:2047. PubMed
6. Perreau M, et al. 2014. J Exp Med. 211:2033. PubMed
7. Luetke-Eversloh M, et al. 2014. PLoS Pathog. 10:1004441. PubMed
8. Zhou J, et al. 2015. J Immunol. 194:4688. PubMed

  • 目录号：2213010
  • 品牌：Sony Biotechnology
  • 规格：100µg
  • 目录价：￥2401.50
  • 市场价格：￥1560.98
  • 会员价格：￥1488.93
  • 数量：

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