PerCP/Cy5.5 anti-human CD205 (DEC-205);Clone#:HD30Host/Isotype:Mouse IgG1, κ   
详细描述
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![]() Human monocyte-derived dendritic cells stained with HD30 PerCP/Cy5.5 |
Description: |
CD205 is a 210 kD C-type lectin transmembrane protein, known as DEC-205. It belongs to macrophage mannose receptor family and is found at high levels on dendritic cells and thymic epithelial cells. Unlike murine CD205, human CD205 is also expressed at low levels on T- and B-cells, NK cells and monocytes. CD205, serves as an endocytic receptor, functions in antigen uptake/processing and clearance of apoptotic cells. |
Other Names: | DEC-205 |
Structure: | Macrophage mannose receptor family, C-type lectin, 210 kD |
Distribution: | High levels on dendritic cells and thymic epithelial cells, low levels on lymphocytes and monocytes |
Function: | Antigen uptake and process |
Antigen References: |
1. Guo M, et al. 2000. Human Immunology 61:729. |
This product or portions thereof is manufactured under license from GE Healthcare under U.S. Patent Numbers 5,268,486; 5,569,587; 5,627,027 and patents or pending applications that are continuations, continuations-in-part, re-examinations, divisionals, reissues or foreign equivalents thereof. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE.
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