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PerCP/Cy5.5 anti-human CD205 (DEC-205);Clone#:HD30Host/Isotype:Mouse IgG1, κ   

详细描述

Clone: HD30
Isotype: Mouse IgG1, κ
Reactivity: Human
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation: The antibody was purified by affinity chromatography, and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Application Notes:

Additional reported applications (for the relevant formats) include: immunohistochemical staining of fixed, frozen sections4 and Western blotting4.

Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cy5.5 has a maximum absorption of 482 nm and 564 nm and a maximum emission of 690 nm.
Application References:

1. Guo M, et al. 2000. Human Immunology 61:729.
2. Cho H, et al. 2007. Physiol Genomics doi:10.1152/physiolgenomics.00051.2006
3. Gurer C, et al. 2008. Blood 112:1231. PubMed
4. Park CG, et al. 2012. J. Immunol. Methods 377:15. (IHC, WB)

Human monocyte-derived dendritic cells stained

Human monocyte-derived dendritic cells stained with HD30 PerCP/Cy5.5

Description:

CD205 is a 210 kD C-type lectin transmembrane protein, known as DEC-205. It belongs to macrophage mannose receptor family and is found at high levels on dendritic cells and thymic epithelial cells. Unlike murine CD205, human CD205 is also expressed at low levels on T- and B-cells, NK cells and monocytes. CD205, serves as an endocytic receptor, functions in antigen uptake/processing and clearance of apoptotic cells.

Other Names: DEC-205
Structure: Macrophage mannose receptor family, C-type lectin, 210 kD
Distribution: High levels on dendritic cells and thymic epithelial cells, low levels on lymphocytes and monocytes
Function: Antigen uptake and process
Antigen References:

1. Guo M, et al. 2000. Human Immunology 61:729.
2. Kato M, et al. 2006. Int. Immunol.
3. Kato M, et al. 2003. J. Biol. Chem. 278(36):34035.
4. Small M and G. Kraal. 2003. Int. Immunol. 15(2):197.
5. Mahnke K, et al. 2000. J. Cell Biol. 151(3):673.


This product or portions thereof is manufactured under license from GE Healthcare under U.S. Patent Numbers 5,268,486; 5,569,587; 5,627,027 and patents or pending applications that are continuations, continuations-in-part, re-examinations, divisionals, reissues or foreign equivalents thereof. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE.
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  • 目录号:2311045
  • 品牌:Sony Biotechnology
  • 规格:25tests
  • 目录价:¥3742.50
  • 市场价格:¥2432.63
  • 会员价格:¥2320.35
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