Pacific Blue™ anti-human CD45RA;Isotype:Mouse IgG2b, κ;Reactivity:Human, Cross-Reactivity: Ch
详细描述
|  | ||||||||||||
| Description | CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines. |
| Formulation | test size: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).microg sizes: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. |
| References | 1. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York. |
